Description
CLEC10A, also known as C-type lectin domain family 10 member A isoform 2, is a C-type lectin superfamily member 14. It is expressed on immature myeloid dendritic cells and alternatively activated macrophages. This protein roles in regulating adaptive and innate immune responses. Also, it binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine, linked to serine or threonine. Recombinant human CLEC10A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques